CRISPR-Cas9 can generate unexpected, heritable mutations

ScienceDaily·Feb 5

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Research on the CRISPR-Cas9 gene editing technology has found that it can generate unexpected, heritable mutations. The technology has shown promise in editing genes to prevent inherited diseases and enhance plant disease resistance, but its use in human embryos has raised concerns about potential unintended consequences. The effectiveness and safety of CRISPR-Cas9 for complex traits and applications, including its potential for use in humans, appears to require further refinement and research.

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