CXCR4, CXCR7 and PBRM1 are responsible for everolimus and cabozantinib resistance in human renal cancer cells
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research has identified cxcr4, cxcr7, and pbrm1 as factors contributing to resistance to the drugs everolimus and cabozantinib in human renal cancer cells. this resistance is a significant issue in the treatment of renal cancer. the specific roles of these factors in resistance are apparently linked to their interaction with the mentioned drugs.