Colorectal cancer is reportedly shifting to affect younger adults in the US at an increasing rate, with some studies indicating that this trend is reversing decades of progress in reducing the disease's burden. The cause of this shift is not specified, but factors such as biological aging and generational changes may be contributing to the rise in early-onset cancer risk. Changes in screening guidelines have led to more cases being detected early in younger adults, but the overall trend is one of rising colorectal cancer rates among young people.