Research has found that combining certain substances with antibiotics can enhance their efficacy against biofilms formed by bacteria such as S. aureus and P. aeruginosa. Various studies have explored different approaches to combating these biofilms, including the use of zinc sulfate, polymeric antibiotics, and surfactant polymer dressings. The effectiveness of these methods in disrupting biofilms and potentiating antibiotic activity is being investigated in different models and contexts.