Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models
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Research on mouse models of Alzheimer's disease has investigated the role of astrocytes and microglia in synapse elimination. The process is said to be dependent on complement C1q and involves both excitatory and inhibitory synapses. The study's findings are related to the progression of Alzheimer's disease in these models.