Research is being conducted to identify the cellular host factors involved in SARS-CoV-2 infection. Studies are exploring various aspects, including entry factors, immune activation, and replication, as well as the role of host factors in the virus's pathogenesis and long-term effects. The use of techniques such as CRISPR knockout screening, genome-wide analysis, and multi-omics analyses is helping to uncover the host factors and pathways that control SARS-CoV-2 infection.