Research is being conducted on the use of various imaging modalities, including pet, spect, cmr, and ct, for the assessment of myocardial ischaemia. Different studies are exploring the effectiveness of these imaging techniques, including their ability to combine anatomy and physiology, and their potential to predict ischemia and impaired myocardial blood flow. The role of these imaging modalities in clinical practice is being evaluated, with some studies focusing on their application in specific areas, such as coronary artery disease and cardio-vascular rare disease clinical trials.