AXL tyrosine kinase inhibitor TP-0903 induces ROS trigger neuroblastoma cell apoptosis via targeting the miR-335-3p/DKK1 expression | Cell Death Discovery
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Researchers have found that the AXL tyrosine kinase inhibitor TP-0903 can induce apoptosis in neuroblastoma cells. This process appears to involve the generation of reactive oxygen species (ROS) and the targeting of the miR-335-3p/DKK1 expression. The study's findings suggest a potential mechanism by which TP-0903 may exert its effects on neuroblastoma cells.