Allosteric inhibition of RAN decreases miR-126 biogenesis in endothelial cells and controls acute myeloid leukemia growth
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Research suggests that inhibiting a certain process can control the growth of acute myeloid leukemia. This inhibition may be related to decreased biogenesis of miR-126 in endothelial cells. The specifics of the mechanism and the substances involved are not entirely clear, with different components potentially playing a role.