Research is being conducted on the role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in various health conditions. Studies have explored its association with conditions such as autoimmune liver disease, vascular disease in type 2 diabetic patients, and coronary artery disease. The enzyme's activity and inhibition are also being investigated in relation to different diseases, including hypercholesterolaemia and neuropsychiatric disorders.