Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres

Nature·Feb 11

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1

Switchable annulation paths to diverse N-bridged bicyclic scaffolds via ligand-directed dicarbonylation

Nature·Jun 9

2

Synthesis of aryl-fused bicyclo[3.1.1]heptanes and validation as naphthyl bioisosteres

Nature·May 6

3

Challenging the Bredt’s rule in an acid catalyzed cationic cyclization to get bicyclo[3.3.1]nonane derivatives

Nature·Nov 26

4

Divergent photochemical ring-replacement of isoxazoles

Nature·Jan 29

5

Construction of azaheterocycles via Pd-catalyzed migratory cycloannulation reaction of unactivated alkenes

Nature·Aug 27