Research is being conducted on the genetic evolution of keratinocytes to cutaneous squamous cell carcinoma, exploring the dynamics of mutational selection and the role of various factors in the development of this type of skin cancer. Studies are investigating the molecular biology and pathogenesis of cutaneous squamous cell carcinoma, including the use of novel 3D tools and animal models. The progression of the disease is being examined, with a focus on identifying driver mutations and gene combinations that contribute to its development.