A large-scale study of 200,453 individuals has provided new insights into the causes and consequences of clonal hematopoiesis. The research has shed light on various aspects of the condition, including its progression to myeloid neoplasms, potential drivers and risk factors, and possible therapeutic strategies. The findings have been reported in multiple studies, which have identified patterns and drivers of clonal hematopoiesis, as well as potential targets for treatment.