Design, synthesis, characterization, pharmacological evaluation and in silico ADMET and molecular docking and dynamics simulations of a novel series of N-substituted pyrazole from chalcone derivatives | Scientific Reports

Nature·Mar 1

✦ NabkaNews BriefAuto-summarized from multiple outlets · verify with the source

Researchers have synthesized and evaluated various novel compounds, including pyrazole derivatives, for their potential pharmacological properties. The compounds have undergone characterization, molecular docking, and biological evaluation for activities such as anti-inflammatory, antimicrobial, and antifungal effects. The specific compounds and their potential uses appear to vary across different studies.

Full coverage

Synthesis, docking, SAR and ADMET evaluation of novel pyrrolo[3,4-c]pyrazole-4,6-dione derivatives

Nature·Jan 6

Pharmacological evaluation as analgesic and anti-inflammatory and molecular docking of newly synthesized nitrogen heterocyclic derivatives

Nature·Dec 20

Synthesis, molecular docking, ADMET studies and biological evaluation of fused pyrazolopyridopyrimidine derivatives as antioxidant and antimicrobial agents

Nature·Dec 11

Design, synthesis, characterization, biological investigation and docking studies of newly synthesized sulphonyl hydrazide and their derivatives

Nature·Nov 11

In-silico studies, synthesis, and pharmacological screening of novel multitarget diphenylpyrazole scaffold as EGFR/BRAF and cyclooxygenase-2 inhibitors

Nature·Dec 23

Synthesis, characterization, computational and biological evaluation of pyrazole hydrazones as promising anti-inflammatory agents

Nature·Nov 23

Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents

Nature·Apr 28

Synthesis, characterization, quantum chemical modelling, molecular docking, in silico and in vitro assessment of 3-(2-bromo-5-fluorophenyl))-1-(thiophen-2-yl)prop-2-en-1-one

Nature·Dec 1

View original report at Nature ↗

Fetching the latest headlines…