Di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis through activating the Ras/Akt/TRHr pathway and inducing hepatic enzymes
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Research suggests that di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis. The disruption is thought to occur through the activation of a specific cellular pathway and the induction of hepatic enzymes. There may be a link between di2-ethylhexyl phthalate exposure and the development and progression of thyroid cancer.