Differential toxicity profile of secreted and processed α-Klotho expression over mineral metabolism and bone microstructure | Scientific Reports
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Research on the α-Klotho gene has yielded findings related to its impact on mineral metabolism and bone microstructure. Some studies suggest that certain forms of α-Klotho may have protective effects, such as guarding against age-dependent memory deficits or mitigating bone injury associated with chronic kidney disease. The specific effects and potential therapeutic applications of α-Klotho are being explored in various studies, including those involving gene therapy and its potential to extend lifespan in certain animal models.