Research is being conducted on the role of macrophages in regulating proinflammatory cytokines, such as Il-1β and Tnf-α, in the context of zebrafish spinal cord regeneration. The study of macrophage function and cytokine regulation is also being explored in other areas, including neuropathic pain, inflammatory responses, and cardiovascular disease. The exact mechanisms and outcomes of these processes are being investigated through various approaches, including in vitro and in silico studies.