Research is exploring the role of neutrophils in tumor immunity and immunotherapy resistance, including their interactions with the tumor microenvironment and potential mechanisms of action. Studies are investigating the complex relationships between neutrophils, other immune cells, and cancer therapies, with some focusing on specific types of cancer, such as hepatocellular carcinoma and ovarian cancer. The findings suggest that neutrophils can have both positive and negative effects on cancer immunity and immunotherapy outcomes, depending on the context and underlying mechanisms.