Fatty acid synthase (FASN) is a tumor-cell-intrinsic metabolic checkpoint restricting T-cell immunity
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Research suggests that fatty acid synthase (FASN) plays a role in restricting T-cell immunity in tumor cells. The relationship between lipid metabolism and the tumor microenvironment is being explored, with studies indicating that metabolic reprogramming can impact the immune landscape. The interaction between metabolic pathways and immune cells in the tumor microenvironment is a complex one, with various factors influencing cancer progression and potential therapy.
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