Ferroptosis is being studied for its potential to inhibit the biological behaviors of glioma cells. Research suggests that ferroptosis may downregulate the transcriptional level of Galectin-9 via extracellular Acetyl-HMGB1, although the specific mechanisms and implications are still being explored. The role of ferroptosis in cancer treatment is a topic of ongoing investigation, with potential applications in various types of cancer, including glioma, osteosarcoma, and hepatocellular carcinoma.