Research suggests that certain microorganisms may help alleviate lipid accumulation caused by high-fructose or high-fat diets. Studies in mice have found that administration of specific bacterial strains can modulate gut microbiota and intestinal barrier function, potentially reversing conditions such as hepatic steatosis. The exact mechanisms and effects of these microorganisms are being explored, with some studies investigating the role of heat-killed bacteria and others examining the impact of dietary fiber on the gut microbiome.