Researchers have been evaluating the use of artificial intelligence in colorectal cancer diagnosis, specifically in testing for microsatellite instability. Studies have been conducted to validate the effectiveness of AI-based tools in analyzing histopathology images and predicting cancer biomarkers. The development and validation of these AI-based tools, such as Deepath-MSI and MSIntuit, may potentially lead to rapid molecular profiling and reduced diagnostic times for colorectal cancer.