Researchers are studying how the Ebola virus persists in the brain, using models such as human cerebral organoids to understand the mechanisms involved. The virus appears to be able to hide and maintain active persistence in the central nervous system, with some studies suggesting it can remain for extended periods, potentially leading to long-term neurological effects. The duration of persistence is not fully clear, with reports ranging from more than 7 years after infection to at least 120 days in brain-like organoids.