A systematic review has been conducted on the immunomodulatory role of mesenchymal stem cell therapy in multiple sclerosis. The review is part of a broader area of research that explores the potential of mesenchymal stem cells to modulate immune responses in various diseases. Mesenchymal stem cell therapy is being studied for its potential therapeutic applications in multiple sclerosis and other conditions, including autoinflammatory diseases, lung diseases, diabetes, and covid-19.