Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme–ubiquitin complex
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Researchers are exploring the use of molecular glue compounds to inhibit certain protein complexes, with potential applications in drug discovery and development. The identification and optimization of these compounds are being aided by advances in high-throughput proteomics and artificial intelligence. The field of molecular glues is rapidly evolving, with potential therapeutic targets and market growth being investigated.
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