Lactobacillus paragasseri LPG-9 reduces placental inflammation in intrahepatic cholestasis of pregnancy by regulating TGR5 in mice
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Research suggests that lactobacillus paragasseri LPG-9 may reduce placental inflammation in intrahepatic cholestasis of pregnancy by regulating TGR5 in mice. The condition is also linked to alterations in gut microbiota, which may contribute to changes in host bile acid metabolism. The relationship between gut microbiota and intrahepatic cholestasis of pregnancy is being studied.