Research suggests that certain non-coding rnas, including meg3, hcn3, and linc01105, may play a role in the development of neuroblastoma by influencing cell proliferation and apoptosis through the hif-1α and p53 pathways. These rnas may have tumor suppressor properties, with meg3 potentially acting as a suppressor in multiple types of cancer. The involvement of these rnas in neuroblastoma pathogenesis is a subject of ongoing study.