A study is comparing the effectiveness of navigational bronchoscopy and transthoracic needle biopsy for diagnosing lung nodules. The research suggests that navigational bronchoscopy may be a safer alternative to transthoracic needle biopsy, with some findings indicating it is as effective. Different methods and technologies, including robotic bronchoscopy and cone-beam CT, are being explored to improve diagnostic accuracy and yield for lung nodule biopsies.