Research suggests that sleep plays a role in the clearance of brain lipids, with some studies indicating that peripheral blood cells are involved in this process. The relationship between sleep, brain health, and the clearance of toxic waste is being explored, with findings implying a connection to mitochondrial homeostasis and overall brain function. The exact mechanisms and cell types involved are still being investigated, with various studies examining the roles of different cell types, including macrophages and glial cells.