Research on mammalian wound healing is exploring various strategies to promote scarless healing, including the use of mRNA therapy and the study of spatiotemporal dynamics in tissues. Studies are utilizing advanced techniques such as machine learning, electrical impedance spectroscopy, and multi-modal microscopy to better understand the complex processes involved in wound healing. The findings are shedding light on the underlying mechanisms, including immune heterogeneity and cellular behavior, that could potentially lead to improved wound healing outcomes.