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PPP2R1A mutations portend improved survival after cancer immunotherapy · NabkaNews

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PPP2R1A mutations portend improved survival after cancer immunotherapy

Nature·Jul 2

✦ NabkaNews BriefAuto-summarized from multiple outlets · verify with the source

Mutations in the PPP2R1A gene have been linked to improved survival in patients undergoing cancer immunotherapy. This association has been observed in various types of cancer, including ovarian and endometrial cancer. The discovery of this genetic marker may contribute to the development of biomarker-driven cancer immunotherapy.

Full coverage

PPP2R1A Mutations Predict Immunotherapy Response

Oncodaily·Aug 21

Towards biomarker-driven cancer immunotherapy: the rising of a protein phosphatase regulator

New genetic marker linked to improved survival with immunotherapy in ovarian and other cancers

UT MD Anderson·Jul 2

PPP2R1A Mutations Associated With Prolonged OS in High-Risk Endometrial Cancer

OncLive·Jan 31

Genetic mutation predicts survival after immunotherapy for ovarian cancer

Volume 644 Issue 8076, 14 August 2025

A pan-cancer analysis of PBAF complex mutations and their association with immunotherapy response

View original report at Nature ↗