Research suggests a link between peripheral insulin resistance and impaired working memory in healthy adults, with studies indicating that it may also affect cerebral glucose metabolism. Other findings imply that insulin resistance may be connected to various metabolic and neuropsychiatric conditions, and that factors such as exercise and nutrient metabolism can influence insulin resistance and related cognitive functions. The relationship between insulin resistance, glucose metabolism, and cognitive health appears to be complex and multifaceted, with different studies exploring its mechanisms and implications in different contexts.