Pleiotropic shared heritability quantifies the shared genetic variance of common diseases

Nature·Jun 9

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Research has identified shared genetic variance among various common diseases, including psychiatric disorders, cardiovascular diseases, and others. Studies have found links between the genetic architecture of conditions such as type 1 diabetes, obesity, and asthma, and other diseases or traits. The shared genetic associations suggest that certain diseases may have common underlying risk factors.

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Shared genetic and neuroimmune architecture links type 1 diabetes with neurocognitive traits

Nature·Mar 13

In-Depth characterization of the shared genetic architecture of suicide attempts with other major psychiatric disorders

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Mapping the genetic landscape across 14 psychiatric disorders

Nature·Dec 10

Genetics identifies obesity as a shared risk factor for co-occurring multiple long-term conditions

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Shared genetic architecture contributes to risk of major cardiovascular diseases

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A genome-wide cross-trait analysis characterizes the shared genetic architecture between lung and gastrointestinal diseases

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View original report at Nature ↗

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