Research is exploring the potential of tissue-derived extracellular vesicles in various medical applications, including drug and vaccine delivery, tissue regeneration, and disease therapy. The use of extracellular vesicles derived from different sources, such as mesenchymal stem cells, red blood cells, and plants, is being investigated for their therapeutic potential. Studies are examining the mechanisms, strategies, and clinical applications of extracellular vesicles in regenerative medicine and the treatment of diseases.