Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

Nature·Jul 30

✦ NabkaNews BriefAuto-summarized from multiple outlets · verify with the source

Research suggests that purine metabolism plays a role in regulating dna repair and therapy resistance in glioblastoma. Other studies also explore the connection between metabolism and cancer therapy resistance in various types of cancer, including pancreatic cancer. The relationship between metabolic pathways and cancer treatment outcomes is being investigated as a potential strategy to overcome therapy resistance.

Full coverage

The oncogenic control of nucleotide synthesis

Nature·Mar 26

The extracellular matrix drives guanylate production and protects pancreatic cancer cells from oxaliplatin-induced DNA damage

Science | AAAS·Dec 12

CUL5-mediated ubiquitination in cancer cell therapy: context-dependent roles, molecular networks, and emerging therapeutic avenues

Frontiers·Mar 24

NANP targeting radiosensitizes glioblastoma through TNFR1 sialylation-driven mesenchymal shift

Nature·Mar 18

Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy

Frontiers·Mar 22

Pentose phosphate pathway fuels cGAS-STING signalling to boost function of intratumoral conventional dendritic cells

Nature·Mar 23

Targeting metabolic reprogramming in glioblastoma as a new strategy to overcome therapy resistance

Frontiers·Feb 25

Roles of nucleotide metabolism in pancreatic cancer

Frontiers·Sep 26

View original report at Nature ↗

Fetching the latest headlines…