Pushing the resolution limit by correcting the Ewald sphere effect in single-particle Cryo-EM reconstructions

Nature·Apr 19

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Researchers are exploring ways to improve the resolution of cryo-electron microscopy (cryo-EM) reconstructions, including correcting the Ewald sphere effect. This has led to the determination of structures at high resolution, including those of viruses and proteins. The outcomes of these efforts include the revelation of new details about the structure and maturation of certain viruses and the development of new imaging algorithms and techniques.

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Pushing the resolution limit of coherent diffractive imaging

Nature·Aug 28

Subnanometer structure of medusavirus capsid during maturation using cryo-electron microscopy

ASM Journals·Aug 28

Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant

Nature·Sep 7

Particle Morphology of Medusavirus Inside and Outside the Cells Reveals a New Maturation Process of Giant Viruses

ASM Journals·Mar 18

An electron counting algorithm improves imaging of proteins with low-acceleration-voltage cryo-electron microscope

Nature·Apr 6

Determining protein structures in cellular lamella at pseudo-atomic resolution by GisSPA

Nature·Mar 15

A novel capsid protein network allows the characteristic internal membrane structure of Marseilleviridae giant viruses

Nature·Dec 11

Structure of intact α-carboxysome specifies role of CsoS2 in shell assembly

Nature·Apr 11

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