Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer | Cell Death & Disease
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Research on breast cancer has led to findings about the role of certain proteins and processes in cancer development and metastasis. The protein ZEB2 is implicated in the invasiveness and tumorigenesis of cancer cells, while another study suggests that low-dose Teniposide may target epithelial-to-mesenchymal transition (EMT) by downregulating ZEB2-driven activation. The interplay between various proteins and cellular processes, including EMT, appears to play a significant role in breast cancer progression and potential resistance to treatment.
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