Research is being conducted on targeting the Met-RIPK1 signaling axis to induce apoptosis and necroptosis in colorectal cancer. Studies have also explored the role of Smac mimetic compounds, IAP antagonists, and IFNγ in regulating apoptosis and cell death pathways. The relationship between these compounds and cancer cell response to chemotherapeutics is also being investigated, with some studies suggesting a dependence on TNF-α.