Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance

Nature·Apr 3

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research on the 3d chromatin architecture in hormone-induced breast cancer and endocrine resistance is being explored. this research may have implications for epigenetic therapy in treating endocrine-resistant breast cancer. the studies involve the integration of various data types, including scHi-C and scRNA-seq, to understand the complex dynamics of the 3d genome.

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The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer

Nature·Jan 5

Integration of scHi-C and scRNA-seq data defines distinct 3D-regulated and biological-context dependent cell subpopulations

Nature·Sep 27

Enhancer–promoter specificity in gene transcription: molecular mechanisms and disease associations

Nature·Apr 25

Sex-specific multi-level 3D genome dynamics in the mouse brain

Nature·Jun 15