The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2
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research suggests that the deubiquitination enzyme usp14 plays a role in the development of gastric cancer. usp14 is reported to enhance the movement of c-myc into the cell nucleus by removing ubiquitin from kpna2. this process may contribute to the growth of gastric cancer tumors.