Research is exploring the role of transposable elements in regulating genomes, particularly in the context of normal and malignant haematopoiesis, as well as other diseases such as cancer. Transposable elements are being studied for their potential impact on stemness, gene expression, and disease development in various types of cancer, including leukemia, colorectal cancer, and gastric cancer. The function of transposable elements in these contexts appears to be complex, with possible roles as enhancers or mediators of genetic effects.