Lane closures are expected to occur on several highways in the area, including I-81 and I-481, although the specific locations and routes affected are not entirely clear. Some closures are planned for overnight, while others may be permanent, such as the closure of a certain exit. The affected areas appear to include towns like Geddes, Salina, Syracuse, and Cicero, with various roads and ramps impacted, including I-690 and route 5.