Two-Step CRISPR Enables Full-Length Mouse Gene Humanisation

CRISPR Medicine News·Jan 14

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1

A scalable two-step genome editing strategy for generating full-length gene-humanized mice at diverse genomic loci

Nature·Jan 14

2

New TECHNO platform enables large-scale human gene integration in mice

Drug Target Review·Jan 19

3

Two-step genome editing enables the creation of full-length humanized mouse models

EurekAlert!·Jan 16

4

HLA matching or CRISPR editing of HLA class I/II enables engraftment and effective function of allogeneic human regulatory T cell therapy in a humanized mouse transplantation model

Nature·Oct 13

5

Massively parallel CRISPR-assisted homologous recombination enables saturation editing of full-length endogenous genes in yeast

Science | AAAS·May 15

6

Programmable RNA-Guided Large DNA Transgenesis by CRISPR/Cas9 and Site-Specific Integrase Bxb1

Frontiers·Jun 25

7

Mouse genome rewriting and tailoring of three important disease loci

Nature·Nov 1

8

Humanising the mouse genome piece by piece

Nature·Apr 23