p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids
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Research on human neural stem cells suggests that p53 plays a role in controlling genomic stability and temporal differentiation. The relationship between p53 and other cellular processes, such as cell cycle control and DNA damage response, is also being explored. However, the exact mechanisms and pathways involved, including the potential roles of other proteins and genes, are still being investigated and appear to be complex.
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