ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Nature·Jul 29

✦ NabkaNews BriefAuto-summarized from multiple outlets · verify with the source

Research has been conducted on the role of ubiquitin ligase components in various cellular processes. The component DDA1 has been found to regulate transcription-coupled repair dynamics. Other studies have explored the functions of different ubiquitin ligase complexes, including their involvement in cell cycle regulation, transcription, and response to DNA damage.

Full coverage

Cryo-EM structure of the human COP1-DET1 ubiquitin ligase complex

Nature·Jan 15

Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation

Nature·Nov 22

The ubiquitin ligase Cullin-1 associates with chromatin and regulates transcription of specific c-MYC target genes

Nature·Aug 18

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Nature·Mar 12

Functional characterisation of components in two Plasmodium falciparum Cullin-RING-Ligase complexes

Nature·Jul 1

Exploration of shared pathogenic factors and causative genes in early-stage endometrial cancer and osteoarthritis

Nature·Jul 1

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway

Nature·Nov 10

The Cullin 4A/B-DDB1-Cereblon E3 Ubiquitin Ligase Complex Mediates the Degradation of CLC-1 Chloride Channels

Nature·May 29

View original report at Nature ↗

Fetching the latest headlines…