CXCL8 is essential for cervical cancer cell acquired radioresistance and acts as a promising therapeutic target in cervical cancer | Scientific Reports

Nature·Jul 1

✦ NabkaNews BriefAuto-summarized from multiple outlets · verify with the source

Research suggests that a factor, possibly related to CXCL8, may play a role in cervical cancer cells becoming resistant to radiation therapy. However, the specific mechanisms and related factors, such as lncRNA CXCL8-203, IL-8, and AP-1 activity, are still being investigated. The findings imply that targeting these factors could potentially improve the effectiveness of radiation therapy in treating cervical cancer.

Full coverage

LncRNA CXCL8-203 down-regulates IL-8 and enhance the radiosensitivity of Siha cells in cervical cancer

Nature·Apr 22

CXCR4, CXCR7 and PBRM1 are responsible for everolimus and cabozantinib resistance in human renal cancer cells

Nature·Mar 28

monocyte emigration impairs the radiation-induced antitumor immune response

Nature·Mar 19

Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity

Nature·Jul 6

Radiation-promoted CDC6 protein stability contributes to radioresistance by regulating senescence and epithelial to mesenchymal transition

Nature·Aug 29

View original report at Nature ↗