Research suggests that inflammation in the bone marrow may contribute to the development and progression of myelodysplastic syndrome, a condition that can lead to leukemia. The inflammatory process appears to involve a complex interaction between T cells and the bone marrow environment, potentially leading to changes in the bone marrow niche. The relationship between inflammation and myelodysplastic syndrome is still being studied, with some findings indicating that it may be possible to identify predictive signs of leukemia years before it develops.