Inflammatory stromal and T cells mediate human bone marrow niche remodeling in clonal hematopoiesis and myelodysplasia

Nature·Nov 18

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Research suggests that inflammation in the bone marrow may play a role in the development of blood diseases, including myelodysplasia and potentially leukemia. Inflammatory cells, including T cells, appear to contribute to changes in the bone marrow that can lead to disease. The relationship between inflammation, bone marrow function, and disease development is complex and the subject of ongoing study.

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