Design, synthesis, and biological evaluation of novel 6-(4-aminopiperidin-1-yl)-substituted benzyl-3-methylpyrimidine-2,4(1H,3H)-dione derivatives as potential anticancer agents targeting thymidylate synthase

Nature·Nov 20

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Researchers have been exploring various compounds as potential anticancer agents, including novel pyrimidine-based derivatives and other synthetic compounds. Some of these compounds have been found to target thymidylate synthase, an enzyme involved in cancer cell growth. The effectiveness and properties of these compounds, such as their cytotoxic evaluation and antimicrobial activity, are being studied and reported.

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