A study using long-read transcriptomics on a diverse human cohort has found ancestry bias in gene annotation, indicating that human gene maps may not fully represent non-European populations. The research has also revealed complex transcriptional activity in certain tissues, such as the placenta and brain, and has explored the relationship between gene expression and psychiatric risk. The findings suggest that incorporating data from diverse ancestry groups can help uncover hidden variation and inform our understanding of human biology and disease mechanisms.